Single Particle Analysis of polydisperse metal-bearing particles in cannabis vape liquids by organic mode ICP-MS

Written By Diana Calle

Z. Gajdosechova, and J. Marleau-Gillette

The popularity of vaping cannabis-derived concentrates has grown rapidly since its legalization in several countries around the world. There is some limited evidence that metal-bearing nanoparticles (NPs) may be present in cannabis vape liquids. Single particle inductively coupled plasma mass spectrometry (ICP-MS) is a technique widely used to obtain critical NP information for samples in aqueous suspension; however, cannabis vape liquids are not water soluble. An approach based on single particle analysis in organic mode ICP-MS is proposed for assessing particle number concentration and particle size distribution in cannabis vape liquids. Cannabis vape liquids from nine cartridges were analyzed for several metal-bearing particles (Fe, Ni, Al, Co, Cu, Cr, V, Zn, Pb, and Sn). All samples analyzed were found to contain a substantial number of NPs.

Journal of Analytical Atomic Spectrometry, 39, (2024):1482-1492, DOI: 10.1039/D4JA00045E

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19 APR 2024
Diana Calle
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